Gastrointestinal dysfunction in Parkinson’s disease
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منابع مشابه
Gastrointestinal Dysfunction in Parkinson’s Disease
Swallowing difficulties and constipation were included in the first description of Parkinsons ́s syndrome from 1817 (Parkinson 1817). Since then, numerous studies have confirmed the magnitude of symptoms and addressed their pathophysiology. In spite of this, much remains to be determined and treatment of gastrointestinal dysfunction in Parkinson ́s disease (PD) is often unsatisfactory. Parkinson ́...
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In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiolog...
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Gastrointestinal dysfunction frequently occurs in liver cirrhosis and increases with disease severity. The major abnormalities are altered gastrointestinal motility, disrupted gut barrier function with increased intestinal permeability and malabsorption. Not only does the presence of these gut abnormalities impair oral intake and lead to malnutrition, they can play a central role in the pathoge...
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Acute gastrointestinal (GI) bleeding is a common indication for admission to the intensive care unit (ICU) in the United States, with over 300,000 admissions per year (1). Most (75%) of these arise from the upper GI tract. Despite advances in critical care medicine, the mortality associated with upper GI bleeding has not changed and remains about 10%, likely due to aging of the population and i...
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Currently, gastrointestinal dysfunctions in Parkinson's disease (PD) are well-recognized problems and are known to be an initial symptom in the pathological process that eventually results in PD. Gastrointestinal symptoms may result from the involvement of either the central or enteric nervous systems, or these symptoms may be side effects of antiparkinsonian medications. Weight loss, excessive...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2020
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-020-09723-5